Kerio has support for multiple IP numbers, however the server will mainly use the first IP, even if you configure a specific domain to use a different IP the server will still communicate on the first ip avaible
. This has a major disadvantage if you want to separate your customers/domains
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Worst case scenario your entire kerio connect server will be blacklisted for one user missbehaved
. Why it cannot keep the same ip as the connection was initiated to is a good question. Its much easier to trace a smtp message if the ip does not change in the handling.